Simcyp Limited is a spin-out from the University of sheffield that informs the processes of drug discovery and development by simulating virtual patient populations to identify individuals at extreme risk.

Simcyp® programs contain databases on human physiological, genetic and epidemiological information. The latter incorperate characteristics of specific disease populations and racial groups. The information is then integrated with human in vitro data generated by the user to predict the population distribution and likelihood of pharmacokinetic parameters (as opposed to single values). Simcyp® programs also contain databases of the in vitro metabolism of drugs that are currently used clinically.